Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 9/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27185446 | 1.00 | STING1 (0.74) | STING1KDM4EMAPTIRAK4LMNA | |
| SCHEMBL30829631 | 0.93 | STING1 (0.69) | STING1KDM4EMAPTIRAK4HSD17B10 | |
| SCHEMBL27185698 | 0.93 | STING1 (0.69) | STING1KDM4EMAPTIRAK4HSD17B10 | |
| SCHEMBL27185529 | 0.90 | STING1 (0.78) | STING1KDM4EMAPTIRAK4LMNA | |
| SCHEMBL27185781 | 0.90 | STING1 (0.75) | STING1KDM4EMAPTIRAK4LMNA | |
| SCHEMBL27185881 | 0.90 | STING1 (0.75) | STING1KDM4EMAPTIRAK4LMNA | |
| SCHEMBL29784478 | 0.90 | STING1 (0.78) | STING1KDM4EMAPTIRAK4LMNA | |
| SCHEMBL29784431 | 0.90 | STING1 (0.75) | STING1KDM4EMAPTIRAK4LMNA | |
| SCHEMBL29784432 | 0.90 | STING1 (0.75) | STING1KDM4EMAPTIRAK4LMNA | |
| SCHEMBL29784479 | 0.90 | STING1 (0.74) | STING1KDM4EMAPTIRAK4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169921-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-08-11 | — | — | WO | disclosed |