Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27185840 | 1.00 | STING1 (0.75) | STING1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL27185484 | 0.91 | STING1 (0.77) | STING1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL29784561 | 0.91 | STING1 (0.77) | STING1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL27185881 | 0.90 | STING1 (0.75) | STING1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL29784431 | 0.90 | STING1 (0.75) | STING1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL29784383 | 0.90 | STING1 (0.68) | STING1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL27185831 | 0.90 | STING1 (0.73) | STING1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL29784464 | 0.90 | STING1 (0.73) | STING1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL27185868 | 0.90 | STING1 (0.68) | STING1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL29784312 | 0.89 | STING1 (0.69) | STING1KDM4EMAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169921-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-08-11 | — | — | WO | disclosed |