Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27229955 | 1.00 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL27229749 | 1.00 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL27229800 | 1.00 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL27229729 | 1.00 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL29784673 | 1.00 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL29784611 | 1.00 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL29784672 | 1.00 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL29784715 | 1.00 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL27232375 | 1.00 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL27229943 | 0.89 | CHRM3 (0.33) | HDAC6HTR3AMEN1KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169985-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |