Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14763458 | 1.00 | ABCB1 (0.58) | ABCB1TAS1R3TAS1R1CYP3A4HPGD | |
| SCHEMBL2684282 | 1.00 | ABCB1 (0.58) | ABCB1TAS1R3TAS1R1CYP3A4HPGD | |
| SCHEMBL2684130 | 1.00 | ABCB1 (0.58) | ABCB1TAS1R3TAS1R1CYP3A4HPGD | |
| SCHEMBL27797503 | 0.95 | ABCB1 (0.52) | ABCB1TAS1R3TAS1R1CYP3A4HPGD | |
| SCHEMBL19946423 | 0.92 | ABCB1 (0.48) | ABCB1TAS1R3TAS1R1CYP3A4 | |
| SCHEMBL10147876 | 0.92 | ABCB1 (0.48) | ABCB1TAS1R3TAS1R1CYP3A4 | |
| SCHEMBL10147831 | 0.92 | ABCB1 (0.48) | ABCB1TAS1R3TAS1R1CYP3A4 | |
| SCHEMBL2681809 | 0.91 | ABCB1 (0.48) | ABCB1TAS1R3TAS1R1CYP3A4HPGD | |
| SCHEMBL19946447 | 0.91 | ABCB1 (0.48) | ABCB1TAS1R3TAS1R1CYP3A4HPGD | |
| SCHEMBL2682613 | 0.90 | ABCB1 (0.62) | ABCB1TAS1R3TAS1R1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357904-B1 | CHIRAL DIACHYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | PRECIGEN INC (US) | 2022-07-06 | — | — | EP | disclosed |