Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779728 | 1.00 | ABCB1 (0.47) | ABCB1CYP3A4HDAC3HDAC1HDAC2 | |
| SCHEMBL29786239 | 1.00 | ABCB1 (0.47) | ABCB1CYP3A4HDAC3HDAC1HDAC2 | |
| SCHEMBL2683613 | 1.00 | ABCB1 (0.47) | ABCB1CYP3A4HDAC3HDAC1HDAC2 | |
| SCHEMBL2683263 | 1.00 | ABCB1 (0.47) | ABCB1CYP3A4HDAC3HDAC1HDAC2 | |
| SCHEMBL16034785 | 0.98 | ABCB1 (0.45) | ABCB1CYP3A4HDAC3HDAC1HDAC2 | |
| SCHEMBL13983597 | 0.93 | ABCB1 (0.41) | ABCB1CYP3A4HDAC3HDAC1HDAC2 | |
| SCHEMBL21867268 | 0.92 | ABCB1 (0.42) | ABCB1CYP3A4HDAC1 | |
| SCHEMBL19946435 | 0.89 | ABCB1 (0.60) | ABCB1CYP3A4 | |
| SCHEMBL4283145 | 0.89 | ABCB1 (0.60) | ABCB1CYP3A4 | |
| SCHEMBL2682193 | 0.89 | ABCB1 (0.60) | ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357904-B1 | CHIRAL DIACHYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | PRECIGEN INC (US) | 2022-07-06 | — | — | EP | disclosed |