Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.58 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | MITF | O75030 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GALR3 | O60755 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29463912 | 1.00 | NPC1 (0.58) | NPC1RAB9AMITFGAAL3MBTL1 | |
| Bromide SCHEMBL30020235 | 1.00 | NPC1 (0.58) | NPC1RAB9AMITFGAAL3MBTL1 | |
| Bromide SCHEMBL31435799 | 1.00 | NPC1 (0.58) | NPC1RAB9AMITFGAAL3MBTL1 | |
| Bromide SCHEMBL30021026 | 1.00 | NPC1 (0.58) | NPC1RAB9AMITFGAAL3MBTL1 | |
| SCHEMBL24938735 | 0.98 | NPC1 (0.60) | NPC1RAB9AMITFGAAL3MBTL1 | |
| SCHEMBL17598817 | 0.98 | NPC1 (0.60) | NPC1RAB9AMITFGAAL3MBTL1 | |
| SCHEMBL11291375 | 0.98 | NPC1 (0.60) | NPC1RAB9AMITFGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL29937101 | 0.96 | NPC1 (0.58) | NPC1RAB9AMITFGAAL3MBTL1 | |
| SCHEMBL11498765 | 0.96 | NPC1 (0.59) | NPC1RAB9AMITFGAAL3MBTL1 | |
| SCHEMBL17598805 | 0.92 | NPC1 (0.55) | NPC1RAB9AMITFGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772376-A | Radically polymerizable adhesion-promoting interlayer compositions and methods of use | PRC-迪索托国际公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-115244102-B | Radically polymerizable adhesion-promoting interlayer compositions and methods of use | PRC-迪索托国际公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115244102-A | Free radical polymerizable adhesion promoting interlayer compositions and methods of use | PRC-迪索托国际公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-110719928-B | Dual cure sealant | PRC-迪索托国际公司 | 2022-08-12 | — | — | CN | disclosed |