SCHEMBL29786802

SCHEMBL29786802

CN1c2ccccc2C(C)(C)C12C=Cc1cc(Br)cc(Br)c1O2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.57
GAA P10253 4/20 0.57
NPSR1 Q6W5P4 4/20 0.57
LMNA P02545 4/20 0.57
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
RECQL P46063 3/20 0.57
TDP1 Q9NUW8 3/20 0.57
ALOX15 P16050 2/20 0.57
ALPG P10696 1/20 0.57
TP53 P04637 1/20 0.57
HSD17B10 Q99714 1/20 0.57
ESR1 P03372 1/20 0.41
THRB P10828 5/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
PKM P14618 2/20 0.40
PLIN1 O60240 1/20 0.40
TSHR P16473 1/20 0.40
PLIN5 Q00G26 1/20 0.40
ABHD5 Q8WTS1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1896651 1.00 MAPT (0.57) MAPTGAANPSR1LMNAMEN1
SCHEMBL29448326 1.00 MAPT (0.57) MAPTGAANPSR1LMNAMEN1
SCHEMBL8680301 0.86 MAPT (0.53) MAPTGAANPSR1LMNAMEN1
SCHEMBL8680969 0.86 MAPT (0.53) MAPTGAANPSR1LMNAMEN1
SCHEMBL8682142 0.85 GAA (0.41) MAPTGAANPSR1LMNAMEN1
SCHEMBL1896282 0.85 MAPT (0.51) MAPTGAANPSR1LMNAMEN1
SCHEMBL29493001 0.85 MAPT (0.51) MAPTGAANPSR1LMNAMEN1
SCHEMBL8684941 0.83 MAPT (0.41) MAPTGAANPSR1LMNAMEN1
SCHEMBL22638027 0.83 GAA (0.52) MAPTGAANPSR1LMNAMEN1
SCHEMBL29466130 0.83 GAA (0.52) MAPTGAANPSR1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118772376-A Radically polymerizable adhesion-promoting interlayer compositions and methods of use PRC-迪索托国际公司 2024-10-15 CN disclosed
CN-115244102-B Radically polymerizable adhesion-promoting interlayer compositions and methods of use PRC-迪索托国际公司 2024-06-18 CN disclosed
EP-4294856-A1 COMPOSITIONS CONTAINING A FREE RADICAL POLYMERIZATION INITIATOR PRC-Desoto International, Inc. (US) 2023-12-27 EP disclosed
CN-117222692-A Mixed dual cure composition PRC-迪索托国际公司 2023-12-12 CN disclosed
CN-117043234-A Composition containing radical polymerization initiator PRC-迪索托国际公司 2023-11-10 CN disclosed
EP-4077464-A2 FREE RADICAL POLYMERIZABLE ADHESION-PROMOTING INTERLAYER COMPOSITIONS AND METHODS OF USE PRC-Desoto International, Inc. (US) 2022-10-26 EP disclosed
CN-115244102-A Free radical polymerizable adhesion promoting interlayer compositions and methods of use PRC-迪索托国际公司 2022-10-25 CN disclosed
CN-115087711-A Adhesion promoting compositions containing organotitanates/zirconates and methods of use PRC-迪索托国际公司 2022-09-20 CN disclosed
WO-2022177863-A1 COMPOSITIONS CONTAINING A FREE RADICAL POLYMERIZATION INITIATOR PRC-DESOTO INTERNATIONAL, INC. (US) 2022-08-25 WO disclosed
CN-110719928-B Dual cure sealant PRC-迪索托国际公司 2022-08-12 CN disclosed