Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 4/20 | 0.78 |
| ▸ | PDE4A | P27815 | 8/20 | 0.49 |
| ▸ | PDE1A | P54750 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | PDE8A | O60658 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PDE9A | O76083 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.47 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23069606 | 1.00 | PDE1B (0.78) | PDE1BPDE4APDE1APDE1CPDE2A | |
| SCHEMBL193846 | 0.88 | PDE1B (0.59) | PDE1BPDE4APDE1APDE1CPDE2A | |
| SCHEMBL193943 | 0.88 | PDE1B (0.60) | PDE1BPDE4APDE1APDE1CPDE2A | |
| SCHEMBL23083001 | 0.87 | PDE1B (0.59) | PDE1BPDE4APDE1APDE1CPDE2A | |
| SCHEMBL29790114 | 0.86 | PDE1B (0.57) | PDE1BPDE4APDE5AALDH1A1POLB | |
| SCHEMBL23069655 | 0.86 | PDE1B (0.57) | PDE1BPDE4APDE5AALDH1A1POLB | |
| SCHEMBL193592 | 0.83 | PDE1B (0.54) | PDE1BPDE4APDE1APDE1CPDE2A | |
| SCHEMBL17502928 | 0.81 | PDE1B (0.68) | PDE1BPDE4APDE1APDE1CPDE2A | |
| SCHEMBL17502931 | 0.80 | PDE1B (0.67) | PDE1BPDE4APDE1APDE1CPDE2A | |
| SCHEMBL17384716 | 0.80 | PDE1B (0.66) | PDE1BPDE4APDE2APDE4DPDE8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410175-B2 | Compounds | INTRA-CELLULAR THERAPIES, INC. (US) | 2025-09-09 | — | — | US | disclosed |
| US-20220356187-A1 | NOVEL COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. | 2022-11-10 | — | — | US | disclosed |
| EP-4025202-A1 | NOVEL COMPOUNDS | Intra-Cellular Therapies, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220356187-A1 | NOVEL COMPOUNDS | DRD1, PDE4A, PDE4D | PDE1B 15/4885PDE4A 2/4885PDE1A 17/4885 |
| US-12410175-B2 | Compounds | PDE4A, PDE4B, DBH | PDE1B 34/4885PDE4A 1/4885PDE1A 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.