Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29789518 | 0.86 | TSHR (0.44) | ACACBTSHRBRPF1KMT2AHPGD | |
| SCHEMBL29790214 | 0.80 | TP53 (0.48) | ACACBTSHRBRPF1KMT2ATP53 | |
| SCHEMBL25256890 | 0.80 | TP53 (0.48) | ACACBTSHRBRPF1KMT2ATP53 | |
| SCHEMBL8297132 | 0.77 | KMT2A (0.39) | TSHRKMT2APOLBMEN1ABCB1 | |
| SCHEMBL6495095 | 0.77 | KMT2A (0.39) | TSHRKMT2APOLBMEN1ABCB1 | |
| SCHEMBL29789574 | 0.77 | TSHR (0.47) | TSHRKMT2AHPGDTP53POLB | |
| SCHEMBL13033929 | 0.77 | TSHR (0.47) | TSHRKMT2AHPGDTP53POLB | |
| SCHEMBL13843619 | 0.75 | BTK (0.38) | TSHRKMT2AHPGDELANETP53 | |
| SCHEMBL5422719 | 0.75 | BTK (0.38) | TSHRKMT2AHPGDELANETP53 | |
| SCHEMBL25438942 | 0.75 | TSHR (0.45) | TSHRKMT2AHPGDELANETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119156393-A | Cyclic compound, preparation method and medical application thereof | 翰森生物有限责任公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-115894606-A | RAS inhibitors | 锐新医药公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114786777-A | RAS inhibitors | 锐新医药公司 | 2022-07-22 | — | — | CN | disclosed |