Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | PARP1 | P09874 | 2/20 | 0.62 |
| ▸ | HTR5A | P47898 | 1/20 | 0.61 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.61 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466239 | 0.86 | TAAR1 (0.96) | TAAR1KDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL169954 | 0.86 | TAAR1 (0.96) | TAAR1KDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL11468065 | 0.85 | KDM4E (0.60) | TAAR1KDM4EALDH1A1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL30741597 | 0.85 | TAAR1 (1.00) | TAAR1KDM4EALDH1A1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL2243782 | 0.85 | TAAR1 (1.00) | TAAR1KDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL32667958 | 0.78 | KDM4E (1.00) | TAAR1KDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL1383033 | 0.78 | KDM4E (1.00) | TAAR1KDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL3045846 | 0.78 | HTR2A (1.00) | TAAR1KDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL29736160 | 0.78 | HTR2A (1.00) | TAAR1KDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL8359331 | 0.77 | PARP1 (1.00) | TAAR1KDM4EHTR2AHTR2CPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200079768-A1 | AZA-DIHYDRO-ACRIDONE DERIVATIVES | ARTAX BIOPHARMA INC. | 2020-03-12 | — | — | US | claimed |
| EP-3375784-A1 | AZA-DIHYDRO-ACRIDONE DERIVATIVES | Artax Biopharma Inc. (US) | 2018-09-19 | — | — | EP | claimed |
| US-20200079768-A1 | AZA-DIHYDRO-ACRIDONE DERIVATIVES | ARTAX BIOPHARMA INC. | 2020-03-12 | — | — | US | disclosed |
| WO-2018170048-A1 | AZA-DIHYDRO-ACRIDONE DERIVATIVES | ARTAX BIOPHARMA, INC. (US) | 2018-09-20 | — | — | WO | disclosed |
| EP-3375784-A1 | AZA-DIHYDRO-ACRIDONE DERIVATIVES | Artax Biopharma Inc. (US) | 2018-09-19 | — | — | EP | disclosed |
| US-7772245-B2 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-20060199829-A1 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS, INC. | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199829-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC2, HDAC11 | TAAR1 4360/4885KDM4E 691/4885ALDH1A1 806/4885 |
| US-20200079768-A1 | AZA-DIHYDRO-ACRIDONE DERIVATIVES | CDKN1A, CD4, MKI67 | TAAR1 552/4885KDM4E 1211/4885ALDH1A1 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.