SCHEMBL29794579

SCHEMBL29794579

CC(Nc1ncc(Br)c(Nc2cc(C3CC3)[nH]n2)n1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 15/20 1.00
NTRK1 P04629 8/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4069157 1.00 IGF1R (1.00) IGF1RNTRK1
SCHEMBL4075877 1.00 IGF1R (1.00) IGF1RNTRK1
SCHEMBL4459019 1.00 IGF1R (1.00) IGF1RNTRK1
SCHEMBL4144686 0.90 NTRK1 (1.00) IGF1RNTRK1
SCHEMBL11349943 0.90 IGF1R (1.00) IGF1RNTRK1
SCHEMBL11344767 0.89 IGF1R (1.00) IGF1RNTRK1
SCHEMBL11344539 0.89 IGF1R (1.00) IGF1RNTRK1
SCHEMBL4164401 0.89 IGF1R (1.00) IGF1RNTRK1
SCHEMBL4152605 0.89 IGF1R (1.00) IGF1RNTRK1
SCHEMBL3338062 0.88 NTRK1 (0.79) IGF1RNTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945378-B Feeder-based and feeder-free stem cell culture systems for stratified epithelial stem cells and related uses thereof 休斯敦大学体系 2024-11-19 CN disclosed
US-20240158756-A1 FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO UNIVERSITY OF HOUSTON SYSTEM (US) 2024-05-16 US disclosed
CN-114945378-A Feeder-layer and feeder-layer-free stem cell culture systems for stratified epithelial stem cells and uses related thereto 休斯敦大学体系 2022-08-26 CN disclosed
EP-4041259-A1 FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO University of Houston System (US) 2022-08-17 EP disclosed