SCHEMBL29794585

SCHEMBL29794585

C[C@H](O)[C@@H](CO)NC(=O)c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 20/20 1.00
JAK2 O60674 16/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29794744 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL29794595 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2693358 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2692435 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2692359 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2692442 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2692350 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL19547470 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2693351 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL4096720 0.95 NTRK1 (1.00) NTRK1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945378-B Feeder-based and feeder-free stem cell culture systems for stratified epithelial stem cells and related uses thereof 休斯敦大学体系 2024-11-19 CN disclosed
CN-114945378-A Feeder-layer and feeder-layer-free stem cell culture systems for stratified epithelial stem cells and uses related thereto 休斯敦大学体系 2022-08-26 CN disclosed
EP-4041259-A1 FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO University of Houston System (US) 2022-08-17 EP disclosed