SCHEMBL29794659

SCHEMBL29794659

OC[C@H](Nc1ncc(Br)c(Nc2cc(C3CC3)n[nH]2)n1)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 8/20 0.71
IGF1R P08069 16/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4240841 1.00 NTRK1 (0.71) NTRK1IGF1R
SCHEMBL4074207 1.00 NTRK1 (0.71) NTRK1IGF1R
SCHEMBL4240838 1.00 NTRK1 (0.71) NTRK1IGF1R
SCHEMBL4068878 0.91 NTRK1 (0.59) NTRK1IGF1R
SCHEMBL4070052 0.91 NTRK1 (0.59) NTRK1IGF1R
SCHEMBL4071051 0.91 NTRK1 (0.59) NTRK1IGF1R
SCHEMBL4074214 0.91 IGF1R (0.71) NTRK1IGF1R
SCHEMBL30010649 0.91 IGF1R (0.71) NTRK1IGF1R
SCHEMBL4067395 0.90 NTRK1 (0.60) NTRK1IGF1R
SCHEMBL27674599 0.90 NTRK1 (0.60) NTRK1IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945378-B Feeder-based and feeder-free stem cell culture systems for stratified epithelial stem cells and related uses thereof 休斯敦大学体系 2024-11-19 CN disclosed
CN-114945378-A Feeder-layer and feeder-layer-free stem cell culture systems for stratified epithelial stem cells and uses related thereto 休斯敦大学体系 2022-08-26 CN disclosed
EP-4041259-A1 FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO University of Houston System (US) 2022-08-17 EP disclosed