SCHEMBL29794675

SCHEMBL29794675

CC(C)(CF)NC(=O)c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NTRK1 P04629 20/20 1.00
▸ JAK2 O60674 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2692152 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2692148 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2693132 0.94 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2693129 0.94 NTRK1 (1.00) NTRK1JAK2
SCHEMBL29794748 0.94 NTRK1 (1.00) NTRK1JAK2
Hydrochloric Acid SCHEMBL2694181 0.92 NTRK1 (0.85) NTRK1JAK2
Hydrochloric Acid SCHEMBL2694182 0.92 NTRK1 (0.85) NTRK1JAK2
SCHEMBL991937 0.92 NTRK1 (1.00) NTRK1JAK2
SCHEMBL991939 0.92 NTRK1 (1.00) NTRK1JAK2
SCHEMBL29794720 0.92 NTRK1 (1.00) NTRK1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945378-A Feeder-layer and feeder-layer-free stem cell culture systems for stratified epithelial stem cells and uses related thereto 休斯敦大学体系 2022-08-26 — — CN disclosed
EP-4041259-A1 FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO University of Houston System (US) 2022-08-17 — — EP disclosed
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