Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 17/20 | 1.00 |
| ▸ | ZAP70 | P43403 | 6/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
| ▸ | AURKB | Q96GD4 | 1/20 | 1.00 |
| ▸ | STAT6 | P42226 | 3/20 | 0.75 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.73 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.71 |
| ▸ | BTK | Q06187 | 1/20 | 0.71 |
| ▸ | ITK | Q08881 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2383949 | 1.00 | SYK (1.00) | SYKZAP70KCNH2AURKBSTAT6 | |
| SCHEMBL1354433 | 0.93 | SYK (0.86) | SYKZAP70KCNH2AURKBSTAT6 | |
| SCHEMBL1354236 | 0.90 | SYK (1.00) | SYKZAP70KCNH2AURKB | |
| SCHEMBL4713176 | 0.89 | SYK (0.81) | SYKZAP70KCNH2AURKBSTAT6 | |
| SCHEMBL4713431 | 0.89 | SYK (0.79) | SYKZAP70KCNH2AURKBSTAT6 | |
| SCHEMBL12137100 | 0.88 | SYK (0.79) | SYKZAP70KCNH2AURKBSTAT6 | |
| SCHEMBL4714843 | 0.88 | SYK (0.78) | SYKZAP70KCNH2AURKBSTAT6 | |
| SCHEMBL374077 | 0.87 | SYK (1.00) | SYKZAP70KCNH2AURKBCAMK1D | |
| SCHEMBL29794822 | 0.87 | SYK (1.00) | SYKZAP70KCNH2AURKBCAMK1D | |
| SCHEMBL4711601 | 0.87 | SYK (0.76) | SYKZAP70KCNH2AURKBSTAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945378-B | Feeder-based and feeder-free stem cell culture systems for stratified epithelial stem cells and related uses thereof | 休斯敦大学体系 | 2024-11-19 | — | — | CN | disclosed |
| CN-114945378-A | Feeder-layer and feeder-layer-free stem cell culture systems for stratified epithelial stem cells and uses related thereto | 休斯敦大学体系 | 2022-08-26 | — | — | CN | disclosed |