SCHEMBL29794792

SCHEMBL29794792

O=C(NC1CC1)c1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 20/20 1.00
JAK2 O60674 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2695077 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2695079 1.00 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2694089 0.97 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2694085 0.97 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2694228 0.90 NTRK1 (1.00) NTRK1JAK2
SCHEMBL19813181 0.90 NTRK1 (1.00) NTRK1JAK2
SCHEMBL2694225 0.90 NTRK1 (1.00) NTRK1JAK2
SCHEMBL460615 0.89 NTRK1 (0.86) NTRK1JAK2
SCHEMBL460905 0.89 NTRK1 (0.86) NTRK1JAK2
SCHEMBL2693744 0.88 NTRK1 (1.00) NTRK1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945378-B Feeder-based and feeder-free stem cell culture systems for stratified epithelial stem cells and related uses thereof 休斯敦大学体系 2024-11-19 CN disclosed
CN-114945378-A Feeder-layer and feeder-layer-free stem cell culture systems for stratified epithelial stem cells and uses related thereto 休斯敦大学体系 2022-08-26 CN disclosed
EP-4041259-A1 FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO University of Houston System (US) 2022-08-17 EP disclosed