Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18151337 | 1.00 | TNF (0.35) | TNFALOX5AP | |
| SCHEMBL29794871 | 0.95 | TNF (0.33) | TNF | |
| SCHEMBL18151990 | 0.95 | TNF (0.33) | TNF | |
| SCHEMBL18150793 | 0.93 | TNF (0.36) | TNF | |
| SCHEMBL18150619 | 0.93 | TNF (0.36) | TNF | |
| SCHEMBL18151633 | 0.92 | TNF (0.31) | TNF | |
| SCHEMBL29794839 | 0.92 | TNF (0.31) | TNF | |
| SCHEMBL18151140 | 0.91 | PIK3CA (0.34) | TNF | |
| SCHEMBL29794948 | 0.91 | TNF (0.32) | TNF | |
| SCHEMBL18151094 | 0.91 | TNF (0.32) | TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4493221-A2 | TARGETED BIFUNCTIONAL DEGRADERS | Yale University (US) | 2025-01-22 | — | — | EP | disclosed |
| CN-119212727-A | Targeted bifunctional degradants | 耶鲁大学 | 2024-12-27 | — | — | CN | disclosed |
| WO-2024182772-A2 | MANNOSE 6-PHOSPHATE RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| WO-2023178199-A2 | TARGETED BIFUNCTIONAL DEGRADERS | YALE UNIVERSITY (US) | 2023-09-21 | — | — | WO | disclosed |
| EP-4041262-A1 | TARGETED BIFUNCTIONAL DEGRADERS | Yale University (US) | 2022-08-17 | — | — | EP | disclosed |