Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22943788 | 1.00 | HDAC6 (0.48) | HDAC6HDAC1HDAC8HDAC3HDAC10 | |
| SCHEMBL22944073 | 0.91 | HDAC6 (0.56) | HDAC6HDAC1HDAC8HDAC3HDAC10 | |
| SCHEMBL22943613 | 0.81 | HDAC6 (0.63) | HDAC6HDAC1HDAC8HDAC3HDAC10 | |
| SCHEMBL22943619 | 0.79 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC3HDAC10 | |
| SCHEMBL26055252 | 0.79 | HDAC6 (0.42) | HDAC6HDAC1HDAC8HDAC3HDAC10 | |
| SCHEMBL22943833 | 0.78 | HDAC6 (0.62) | HDAC6HDAC1HDAC8HDAC3HDAC10 | |
| SCHEMBL29784696 | 0.78 | HDAC6 (0.41) | HDAC6HDAC1HDAC8HDAC4HDAC7 | |
| SCHEMBL27230058 | 0.78 | HDAC6 (0.41) | HDAC6HDAC1HDAC8HDAC4HDAC7 | |
| SCHEMBL29784582 | 0.78 | HDAC6 (0.41) | HDAC6HDAC1HDAC8HDAC4HDAC7 | |
| SCHEMBL27229793 | 0.78 | HDAC6 (0.41) | HDAC6HDAC1HDAC8HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528767-B2 | HDAC6 inhibitors and uses thereof | EIKONIZO THERAPEUTICS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20220281814-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2022-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281814-A1 | HDAC6 INHIBITORS AND USES THEREOF | HDAC6, HDAC1, HDAC5 | HDAC6 1/4885HDAC1 2/4885HDAC8 8/4885 |
| US-12528767-B2 | HDAC6 inhibitors and uses thereof | HDAC6, HDAC1, HDAC11 | HDAC6 1/4885HDAC1 2/4885HDAC8 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.