Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 9/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28945626 | 1.00 | ASAH1 (0.67) | ASAH1SMN1; SMN2HTTCYP1A2CYP3A4 | |
| SCHEMBL28794759 | 0.84 | ASAH1 (0.64) | ASAH1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL29795566 | 0.84 | ASAH1 (0.64) | ASAH1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL23122842 | 0.83 | ASAH1 (0.83) | ASAH1SMN1; SMN2HTTCYP1A2CYP3A4 | |
| SCHEMBL29795449 | 0.83 | ASAH1 (0.83) | ASAH1SMN1; SMN2HTTCYP1A2CYP3A4 | |
| SCHEMBL29795398 | 0.81 | ASAH1 (0.93) | ASAH1SMN1; SMN2LMNAL3MBTL1MAPK1 | |
| SCHEMBL28794797 | 0.81 | ASAH1 (0.93) | ASAH1SMN1; SMN2LMNAL3MBTL1MAPK1 | |
| SCHEMBL29795580 | 0.80 | ASAH1 (1.00) | ASAH1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL29795462 | 0.80 | ASAH1 (0.64) | ASAH1SMN1; SMN2KMT2A | |
| SCHEMBL29795633 | 0.80 | ASAH1 (1.00) | ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031532-A1 | SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | Bial-R&D Investments, S.A. (PT) | 2022-07-27 | — | — | EP | disclosed |