Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 9/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29795596 | 0.90 | ASAH1 (0.63) | ASAH1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL29795449 | 0.86 | ASAH1 (0.83) | ASAH1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23122842 | 0.86 | ASAH1 (0.83) | ASAH1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL29795498 | 0.84 | ASAH1 (0.65) | ASAH1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28794578 | 0.84 | ASAH1 (0.65) | ASAH1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23124361 | 0.82 | ASAH1 (0.54) | ASAH1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23123367 | 0.80 | ASAH1 (0.54) | ASAH1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23122802 | 0.80 | ASAH1 (0.56) | ASAH1RAB9AALDH1A1CYP1A2BCHE | |
| SCHEMBL28945618 | 0.80 | ASAH1 (0.62) | ASAH1RAB9ANPC1ALDH1A1CYP1A2 | |
| SCHEMBL29795660 | 0.80 | ASAH1 (0.62) | ASAH1RAB9ANPC1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031532-A1 | SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | Bial-R&D Investments, S.A. (PT) | 2022-07-27 | — | — | EP | disclosed |