Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28794558 | 1.00 | ASAH1 (0.62) | ASAH1HPGDMAPK1KMT2ALMNA | |
| SCHEMBL28794626 | 0.90 | ASAH1 (0.62) | ASAH1HPGDMAPK1KMT2ALMNA | |
| SCHEMBL29795599 | 0.90 | ASAH1 (0.62) | ASAH1HPGDMAPK1KMT2ALMNA | |
| SCHEMBL23122904 | 0.84 | ASAH1 (0.59) | ASAH1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL23122514 | 0.83 | ASAH1 (0.60) | ASAH1HPGDKMT2ALMNAMEN1 | |
| Carbamic Acid SCHEMBL9589517 | 0.82 | ASAH1 (0.59) | ASAH1HPGDKMT2ALMNATP53 | |
| SCHEMBL10654951 | 0.82 | ASAH1 (0.90) | ASAH1HPGDKMT2A | |
| SCHEMBL23123402 | 0.82 | ASAH1 (0.56) | ASAH1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL29795660 | 0.81 | ASAH1 (0.62) | ASAH1LMNATP53 | |
| SCHEMBL28945618 | 0.81 | ASAH1 (0.62) | ASAH1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031532-A1 | SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | Bial-R&D Investments, S.A. (PT) | 2022-07-27 | — | — | EP | disclosed |