Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.68 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30313967 | 0.95 | BCL2 (0.69) | BCL2BCL2L1 | |
| SCHEMBL29657435 | 0.93 | BCL2 (0.72) | BCL2BCL2L1 | |
| SCHEMBL30314177 | 0.93 | BCL2 (0.70) | BCL2BCL2L1 | |
| SCHEMBL29657349 | 0.93 | BCL2 (0.70) | BCL2BCL2L1 | |
| SCHEMBL2725176 | 0.93 | BCL2 (0.70) | BCL2BCL2L1 | |
| SCHEMBL2727376 | 0.93 | BCL2 (0.70) | BCL2BCL2L1 | |
| SCHEMBL29944585 | 0.91 | BCL2 (0.67) | BCL2BCL2L1 | |
| SCHEMBL1871052 | 0.91 | BCL2 (0.74) | BCL2BCL2L1 | |
| SCHEMBL29403314 | 0.91 | BCL2 (0.74) | BCL2BCL2L1 | |
| SCHEMBL30314109 | 0.91 | BCL2 (0.70) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114786679-A | Combination therapy with Vernetork and TIM-3 inhibitors | 诺华股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114786680-A | TIM-3 inhibitors and uses thereof | 诺华股份有限公司 | 2022-07-22 | — | — | CN | disclosed |