Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.60 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.55 |
| ▸ | BRAF | P15056 | 3/20 | 0.52 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.52 |
| ▸ | RAF1 | P04049 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.52 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.52 |
| ▸ | NEK2 | P51955 | 2/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.52 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.52 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.52 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.52 |
| ▸ | NEK11 | Q8NG66 | 2/20 | 0.52 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.52 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | KRAS | P01116 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20408849 | 1.00 | CYP2C9 (0.60) | CYP2C9MAP2K4BRAFRIPK2RAF1 | |
| SCHEMBL20408819 | 0.96 | CYP2C9 (0.60) | CYP2C9MAP2K4BRAFRIPK2RAF1 | |
| SCHEMBL23510279 | 0.91 | CYP2C9 (0.66) | CYP2C9MAP2K4BRAFRIPK2RAF1 | |
| SCHEMBL20408843 | 0.89 | CYP2C9 (0.65) | CYP2C9MAP2K4BRAFRIPK2RAF1 | |
| SCHEMBL20408813 | 0.89 | CYP2C9 (0.52) | CYP2C9MAP2K4BRAFRIPK2RAF1 | |
| SCHEMBL29898577 | 0.88 | CYP2C9 (0.52) | CYP2C9MAP2K4BRAFRIPK2RAF1 | |
| SCHEMBL21624479 | 0.88 | CYP2C9 (0.52) | CYP2C9MAP2K4BRAFRIPK2RAF1 | |
| SCHEMBL24523148 | 0.86 | CYP2C9 (0.47) | CYP2C9MAP2K4BRAFRIPK2RAF1 | |
| SCHEMBL20399259 | 0.85 | BRAF (0.73) | CYP2C9MAP2K4BRAFRIPK2RAF1 | |
| SCHEMBL20408845 | 0.85 | MAP2K4 (0.75) | CYP2C9MAP2K4BRAFRIPK2RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110291089-B | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing liver cell death | 海帕瑞吉尼克斯股份有限公司 | 2022-05-27 | — | — | CN | claimed |