Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 3/20 | 0.82 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.82 |
| ▸ | RAF1 | P04049 | 2/20 | 0.82 |
| ▸ | KDR | P35968 | 2/20 | 0.82 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.82 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.82 |
| ▸ | NEK2 | P51955 | 2/20 | 0.82 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.82 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.82 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.82 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.82 |
| ▸ | NEK11 | Q8NG66 | 2/20 | 0.82 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.82 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.82 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.82 |
| ▸ | PLK4 | O00444 | 1/20 | 0.82 |
| ▸ | PIR | O00625 | 1/20 | 0.82 |
| ▸ | AURKA | O14965 | 1/20 | 0.82 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.82 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294160 | 1.00 | BRAF (0.82) | BRAFRIPK2RAF1KDRMAP2K2 | |
| SCHEMBL299371 | 0.95 | BRAF (0.73) | BRAFRIPK2RAF1KDRMAP2K2 | |
| SCHEMBL7869149 | 0.94 | BRAF (0.71) | BRAFRIPK2RAF1KDRMAP2K2 | |
| SCHEMBL298054 | 0.91 | BRAF (0.73) | BRAFRIPK2RAF1KDRMAP2K2 | |
| SCHEMBL16066437 | 0.91 | BRAF (0.68) | BRAFRIPK2RAF1KDRMAP2K2 | |
| SCHEMBL299440 | 0.91 | BRAF (0.73) | BRAFRIPK2RAF1KDRMAP2K2 | |
| SCHEMBL298282 | 0.91 | BRAF (0.84) | BRAFRIPK2RAF1KDRMAP2K2 | |
| SCHEMBL20294639 | 0.90 | BRAF (0.67) | BRAFRIPK2RAF1KDRMAP2K2 | |
| SCHEMBL298349 | 0.90 | BRAF (0.83) | BRAFRIPK2RAF1KDRMAP2K2 | |
| SCHEMBL299672 | 0.90 | BRAF (0.83) | BRAFRIPK2RAF1KDRMAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121851005-A | Synthesis method of N- [3- [ (5-bromo-1H-pyrrolo [2,3-B ] pyridin-3-yl) carbonyl ] -2, 4-difluorophenyl ] -1-propanesulfonamide | 安徽大学 | 2026-04-14 | — | — | CN | disclosed |
| CN-121851005-A | Synthesis method of N- [3- [ (5-bromo-1H-pyrrolo [2,3-B ] pyridin-3-yl) carbonyl ] -2, 4-difluorophenyl ] -1-propanesulfonamide | 安徽大学 | 2026-04-14 | — | — | CN | disclosed |
| CN-112424201-B | Protein kinase inhibitors that promote liver regeneration or reduce or prevent hepatocyte death | 海帕瑞吉尼克斯股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-110291089-B | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing liver cell death | 海帕瑞吉尼克斯股份有限公司 | 2022-05-27 | — | — | CN | disclosed |