Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 16/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.56 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.56 |
| ▸ | ITGB6 | P18564 | 5/20 | 0.55 |
| ▸ | ITGB8 | P26012 | 5/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142512 | 1.00 | ITGAV (0.56) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL20142509 | 1.00 | ITGAV (0.56) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL20140372 | 0.91 | ITGAV (0.56) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL20140379 | 0.91 | ITGAV (0.56) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL20140326 | 0.89 | ITGAV (0.67) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL20140330 | 0.89 | ITGAV (0.67) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL21294618 | 0.89 | ITGAV (0.67) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL23559116 | 0.89 | ITGAV (0.49) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL29860393 | 0.89 | ITGAV (0.49) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL20153357 | 0.89 | ITGAV (0.49) | ITGAVITGB3ITGB1ITGA5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167935-B | 3-substituted propionic acids as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-05-27 | — | — | CN | claimed |
| CN-110167935-B | 3-substituted propionic acids as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-05-27 | — | — | CN | disclosed |