Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.72 |
| ▸ | ITGB3 | P05106 | 19/20 | 0.72 |
| ▸ | ITGB6 | P18564 | 9/20 | 0.71 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.62 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.62 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.62 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21294615 | 1.00 | ITGAV (0.72) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL29797278 | 1.00 | ITGAV (0.72) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL21294610 | 1.00 | ITGAV (0.72) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL20141061 | 1.00 | ITGAV (0.72) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL29797149 | 1.00 | ITGAV (0.72) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL20142039 | 0.98 | ITGAV (0.73) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL20140515 | 0.98 | ITGAV (0.73) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL29797084 | 0.98 | ITGAV (0.73) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL20140510 | 0.98 | ITGAV (0.73) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL29797094 | 0.98 | ITGAV (0.73) | ITGAVITGB3ITGB6ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167935-B | 3-substituted propionic acids as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-05-27 | — | — | CN | claimed |