Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.45 |
| ▸ | EGFR | P00533 | 6/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.44 |
| ▸ | STK4 | Q13043 | 6/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742017 | 0.84 | SRC (0.59) | SRCEGFRERBB2STK4MAP2K1 | |
| SCHEMBL13503087 | 0.82 | SRC (0.49) | SRCEGFRERBB2STK4MAP2K1 | |
| SCHEMBL6381695 | 0.79 | SRC (0.62) | SRCEGFRERBB2 | |
| SCHEMBL5459297 | 0.79 | SRC (0.62) | SRCEGFRERBB2 | |
| SCHEMBL28557672 | 0.77 | SRC (0.50) | SRCEGFRERBB2STK4 | |
| SCHEMBL4865201 | 0.77 | EGFR (0.55) | SRCEGFRERBB2STK4 | |
| SCHEMBL1892242 | 0.74 | SRC (0.45) | SRCEGFRERBB2STK4 | |
| SCHEMBL29590073 | 0.73 | SRC (0.62) | SRCEGFRERBB2 | |
| SCHEMBL1893090 | 0.73 | SRC (0.62) | SRCEGFRERBB2 | |
| SCHEMBL2129771 | 0.73 | STK4 (0.71) | EGFRERBB2STK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112694439-B | Phenyl acrylamide quinoline derivative and preparation method and application thereof | 河南省医药科学研究院 | 2022-08-30 | — | — | CN | disclosed |