Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 10/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 10/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 10/20 | 1.00 |
| ▸ | PDE5A | O76074 | 3/20 | 1.00 |
| ▸ | PDE1A | P54750 | 3/20 | 1.00 |
| ▸ | PDE1B | Q01064 | 3/20 | 1.00 |
| ▸ | PDE1C | Q14123 | 3/20 | 1.00 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.66 |
| ▸ | YTHDC1 | Q96MU7 | 7/20 | 0.62 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | MERTK | Q12866 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185397 | 1.00 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL3141400 | 0.90 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL3141383 | 0.88 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL9738428 | 0.87 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL3146230 | 0.86 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL3133509 | 0.86 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL1321678 | 0.86 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL27993590 | 0.85 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL4460149 | 0.85 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL3133797 | 0.84 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325465-A | Biphenyl substituted epithelial sodium channel blocking compounds | 帕里昂科学公司 | 2025-01-17 | — | — | CN | disclosed |
| EP-4469441-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | Parion Sciences, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146892-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146896-A1 | BICYCLIC-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-110840847-B | Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases | 沃泰克斯药物股份有限公司 | 2022-07-29 | — | — | CN | disclosed |