Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28590532 | 1.00 | CYP1A2 (0.50) | CYP1A2KMT2AMEN1CA12CA1 | |
| SCHEMBL28592370 | 0.90 | CYP1A2 (0.49) | CYP1A2KMT2AMEN1CA12CA1 | |
| SCHEMBL30572436 | 0.90 | KDM4E (0.49) | CYP1A2KMT2AMEN1CA12CA1 | |
| SCHEMBL30572385 | 0.90 | KDM4E (0.49) | CYP1A2KMT2AMEN1CA12CA1 | |
| SCHEMBL28590535 | 0.87 | KDM4E (0.54) | CYP1A2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29799082 | 0.87 | KDM4E (0.54) | CYP1A2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL5805793 | 0.82 | KMT2A (0.47) | CYP1A2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1063212 | 0.82 | KDM4E (0.59) | CYP1A2KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL29799068 | 0.82 | KDM4E (0.59) | CYP1A2KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL165394 | 0.81 | KDM4E (0.47) | CYP1A2KMT2AMEN1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121435-B | Synthetic method of 2, 4-dichloroquinoline compound | 辽宁大学 | 2022-08-30 | — | — | CN | disclosed |