Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 4/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26232004 | 1.00 | KMT2A (0.51) | KMT2APTPN1TLR2MDM4TP53 | |
| SCHEMBL26689394 | 0.94 | KMT2A (0.53) | KMT2APTPN1TLR2MDM4TP53 | |
| SCHEMBL26689238 | 0.94 | KMT2A (0.53) | KMT2APTPN1TLR2MDM4TP53 | |
| SCHEMBL26689241 | 0.94 | KMT2A (0.53) | KMT2APTPN1TLR2MDM4TP53 | |
| SCHEMBL26689396 | 0.94 | KMT2A (0.53) | KMT2APTPN1TLR2MDM4TP53 | |
| SCHEMBL31287180 | 0.92 | KMT2A (0.50) | KMT2APTPN1TLR2CASP3 | |
| SCHEMBL26232021 | 0.92 | KMT2A (0.50) | KMT2APTPN1TLR2CASP3 | |
| SCHEMBL31648532 | 0.92 | KMT2A (0.50) | KMT2APTPN1TLR2CASP3 | |
| SCHEMBL29799591 | 0.92 | KMT2A (0.50) | KMT2APTPN1TLR2CASP3 | |
| SCHEMBL26981156 | 0.92 | TLR2 (0.51) | KMT2APTPN1TLR2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301415-A1 | BRANCHED LINKERS FOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | R.P. Scherer Technologies, LLC (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022187370-A1 | BRANCHED LINKERS FOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | R.P. SCHERER TECHNOLOGIES, LLC (US) | 2022-09-09 | — | — | WO | disclosed |