Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38225 | 0.87 | SLC7A5 (0.55) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL38224 | 0.87 | SLC7A5 (0.55) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL21899391 | 0.87 | SLC7A5 (0.55) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL5352342 | 0.86 | SLC7A5 (0.58) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL9181514 | 0.86 | PPARG (0.44) | SLC7A5ESR1BLM | |
| SCHEMBL9177995 | 0.85 | ALPI (0.55) | SLC7A5FOLH1BLMPOLB | |
| SCHEMBL27626196 | 0.85 | ALPI (0.55) | SLC7A5FOLH1BLMPOLB | |
| SCHEMBL1081375 | 0.84 | SLC7A5 (0.51) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL27669804 | 0.84 | SLC7A5 (0.51) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL1081374 | 0.84 | SLC7A5 (0.51) | SLC7A5TAAR1SLC6A2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805528-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2022-07-29 | — | — | CN | disclosed |