Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 17/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743739 | 1.00 | MAP4K1 (0.58) | MAP4K1ALKPTK2 | |
| SCHEMBL29800959 | 0.86 | MAP4K1 (0.57) | MAP4K1ALKPTK2 | |
| SCHEMBL31378021 | 0.85 | MAP4K1 (0.55) | MAP4K1ALKPTK2 | |
| SCHEMBL29651308 | 0.85 | MAP4K1 (0.65) | MAP4K1ALK | |
| SCHEMBL22864782 | 0.83 | MAP4K1 (0.63) | MAP4K1ALK | |
| SCHEMBL29651061 | 0.83 | MAP4K1 (0.63) | MAP4K1ALK | |
| SCHEMBL25947626 | 0.83 | MAP4K1 (0.63) | MAP4K1ALK | |
| SCHEMBL29651313 | 0.82 | MAP4K1 (0.60) | MAP4K1ALK | |
| SCHEMBL22864581 | 0.82 | MAP4K1 (0.60) | MAP4K1ALK | |
| SCHEMBL22864471 | 0.82 | MAP4K1 (0.62) | MAP4K1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555585-A | HPK1 inhibitors and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2022-05-27 | — | — | CN | disclosed |