Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SCN4A | P35499 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210148 | 1.00 | AXL (0.60) | AXLGFERSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL360218 | 0.84 | AXL (0.53) | AXLGFERSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL3104846 | 0.84 | GAA (0.53) | AXLGFERSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL1638626 | 0.84 | AXL (0.53) | AXLGFERSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL30002611 | 0.84 | SMN1; SMN2 (0.72) | AXLGFERSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL4071678 | 0.84 | AXL (0.53) | AXLGFERSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL1829710 | 0.84 | AXL (0.53) | AXLGFERSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL19709634 | 0.84 | AXL (0.53) | AXLGFERSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL2911354 | 0.84 | SMN1; SMN2 (0.72) | AXLGFERSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL9885168 | 0.84 | SMN1; SMN2 (0.71) | AXLGFERSMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3758697-B1 | NOVEL ANTIMYCOBACTERIAL HETEROCYCLIC AMIDES | CRESTONE INC (US) | 2024-10-16 | — | — | EP | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-109535155-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2022-07-12 | — | — | CN | disclosed |