SCHEMBL29801587

SCHEMBL29801587

Cc1cc(Sc2ccc(OCc3ccc(C(F)(F)F)cc3)c(C)c2)ccc1OCC(=O)O

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.76
PPARA Q07869 2/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2872277 1.00 PPARD (0.76) PPARDPPARA
SCHEMBL5969562 0.94 PPARD (0.68) PPARDPPARA
SCHEMBL2871407 0.94 PPARD (0.83) PPARDPPARA
SCHEMBL13512201 0.94 PPARD (0.83) PPARDPPARA
SCHEMBL2868162 0.91 PPARD (0.65) PPARDPPARA
SCHEMBL13513911 0.89 PPARD (0.68) PPARDPPARA
SCHEMBL13512209 0.88 PPARD (0.64) PPARDPPARA
SCHEMBL13513909 0.88 FFAR4 (0.66) PPARDPPARA
SCHEMBL13513908 0.87 PPARD (0.67) PPARDPPARA
SCHEMBL5507481 0.86 PPARD (1.00) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4031124-A1 USE OF A PPAR-DELTA AGONIST IN THE TREATMENT OF KIDNEY DISEASE Reneo Pharmaceuticals, Inc. (US) 2022-07-27 EP claimed
EP-4031124-A1 USE OF A PPAR-DELTA AGONIST IN THE TREATMENT OF KIDNEY DISEASE Reneo Pharmaceuticals, Inc. (US) 2022-07-27 EP disclosed