Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669351 | 1.00 | MEN1 (0.51) | MEN1KMT2AHDAC3HDAC8MAPT | |
| SCHEMBL29802893 | 0.91 | MAPT (0.46) | MEN1KMT2AHDAC3HDAC8MAPT | |
| SCHEMBL29803071 | 0.90 | MEN1 (0.47) | MEN1KMT2AHDAC3HDAC8MAPT | |
| SCHEMBL24670306 | 0.87 | TMPRSS2 (0.43) | MEN1KMT2AHDAC3HDAC8MAPT | |
| SCHEMBL24669978 | 0.81 | MAPT (0.64) | MEN1KMT2AHDAC8MAPTALDH1A1 | |
| SCHEMBL24891879 | 0.81 | MAPT (0.64) | MEN1KMT2AHDAC8MAPTALDH1A1 | |
| SCHEMBL24670765 | 0.81 | KMT2A (0.60) | MEN1KMT2AMAPTALDH1A1CYP2C9 | |
| SCHEMBL29802966 | 0.81 | MAPT (0.55) | MEN1KMT2AMAPTALDH1A1CYP2C9 | |
| SCHEMBL24670708 | 0.80 | MEN1 (0.55) | MEN1KMT2AHDAC3HDAC8MAPT | |
| SCHEMBL24891925 | 0.79 | NPC1 (0.60) | MEN1KMT2AMAPTALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |