Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | QDPR | P09417 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669202 | 0.93 | MAPKAPK2 (0.49) | MAPKAPK2NAMPTHTR2CPTPN1QDPR | |
| Trifluoroacetic Acid SCHEMBL29803728 | 0.90 | MAPKAPK2 (0.44) | MAPKAPK2NAMPTP2RY14HTR2CPTPN1 | |
| Trifluoroacetic Acid SCHEMBL29803413 | 0.89 | PTPN1 (0.47) | MAPKAPK2NAMPTP2RY14PTPN1QDPR | |
| SCHEMBL24669925 | 0.83 | MAPKAPK2 (0.48) | MAPKAPK2NAMPTP2RY14HTR2CQDPR | |
| Trifluoroacetic Acid SCHEMBL29803774 | 0.81 | MAPKAPK2 (0.43) | MAPKAPK2NAMPTP2RY14HTR2CQDPR | |
| Trifluoroacetic Acid SCHEMBL29803754 | 0.81 | MAPKAPK2 (0.46) | MAPKAPK2NAMPTP2RY14HTR2CQDPR | |
| SCHEMBL24670491 | 0.81 | MAPKAPK2 (0.48) | MAPKAPK2NAMPTPTPN1QDPR | |
| Trifluoroacetic Acid SCHEMBL29803775 | 0.80 | NAMPT (0.45) | MAPKAPK2NAMPTP2RY14HTR2CHTR6 | |
| Trifluoroacetic Acid SCHEMBL29803429 | 0.78 | NPC1 (0.40) | NAMPTKDM4ENPC1LMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL29803386 | 0.76 | MAPKAPK2 (0.46) | MAPKAPK2NAMPTPTPN1QDPRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |