Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 4/20 | 0.41 |
| ▸ | NAMPT | P43490 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669952 | 0.94 | TMPRSS2 (0.45) | TMPRSS2NAMPTALDH1A1HPGDNPC1 | |
| Trifluoroacetic Acid SCHEMBL29803653 | 0.85 | TMPRSS2 (0.37) | TMPRSS2NAMPTALDH1A1HPGDNPC1 | |
| SCHEMBL24670896 | 0.81 | TMPRSS2 (0.46) | TMPRSS2NAMPTALDH1A1HPGDNPC1 | |
| SCHEMBL24667821 | 0.81 | TMPRSS2 (0.54) | TMPRSS2NAMPTALDH1A1HPGDNPC1 | |
| SCHEMBL24670895 | 0.80 | TMPRSS2 (0.44) | TMPRSS2NAMPTALDH1A1HPGDNPC1 | |
| SCHEMBL24671084 | 0.78 | TMPRSS2 (0.41) | TMPRSS2NAMPTALDH1A1HPGDALOX15 | |
| SCHEMBL24669387 | 0.78 | TMPRSS2 (0.45) | TMPRSS2NAMPTALDH1A1HPGDNPC1 | |
| SCHEMBL24891885 | 0.78 | TMPRSS2 (0.45) | TMPRSS2NAMPTALDH1A1HPGDNPC1 | |
| SCHEMBL29803288 | 0.76 | NAMPT (0.54) | NAMPTALDH1A1HPGDSMN1; SMN2JAK2 | |
| Trifluoroacetic Acid SCHEMBL29803611 | 0.76 | MAPT (0.42) | TMPRSS2NAMPTALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |