Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23356395 | 1.00 | SCN8A (0.46) | SCN8ASCN10AMRGPRX4 | |
| SCHEMBL30678495 | 0.89 | USP2 (0.48) | SCN8ASCN10A | |
| SCHEMBL31344141 | 0.89 | SCN8A (0.43) | SCN8ASCN10A | |
| SCHEMBL23356296 | 0.89 | SCN8A (0.43) | SCN8ASCN10A | |
| SCHEMBL24683830 | 0.88 | SCN8A (0.47) | SCN8ASCN10A | |
| SCHEMBL30553098 | 0.88 | SCN8A (0.47) | SCN8ASCN10A | |
| SCHEMBL23356426 | 0.87 | SCN8A (0.47) | SCN8ASCN10A | |
| SCHEMBL31344164 | 0.87 | SCN8A (0.47) | SCN8ASCN10A | |
| SCHEMBL4448828 | 0.82 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL15918159 | 0.82 | SCN8A (0.60) | SCN8ASCN10AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689633-B | For inhibiting Nav1.8 Pyridinecarboxamide Compounds | 利伯研究所公司 | 2025-01-24 | — | — | CN | disclosed |
| EP-4304585-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| CN-117062607-A | Methyl substituted pyridine and pyridazine compounds, derivatives thereof and methods of use thereof | 拉堤果生物医疗股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| WO-2022192487-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2022-09-15 | — | — | WO | disclosed |