Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 15/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 10/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.51 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146190 | 0.82 | PRKCQ (0.61) | PRKCQPRKCD | |
| SCHEMBL2928987 | 0.79 | PRKCQ (0.59) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2980462 | 0.76 | PIK3CA (0.52) | PRKCQPRKCDPIK3CAPIK3CDEGFR | |
| SCHEMBL2975973 | 0.74 | PRKCQ (0.55) | PRKCQPRKCDPRKCHPRKCEEGFR | |
| SCHEMBL2986283 | 0.73 | PRKCQ (0.56) | PRKCQPRKCDPIK3CAPRKCHPRKCE | |
| SCHEMBL2936072 | 0.73 | PRKCQ (0.76) | PRKCQPRKCD | |
| SCHEMBL2934672 | 0.73 | PRKCQ (0.76) | PRKCQPRKCD | |
| SCHEMBL2976690 | 0.73 | PRKCQ (0.69) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2982490 | 0.73 | PRKCQ (0.61) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2984262 | 0.73 | PRKCQ (0.55) | PRKCQPRKCDPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781591-B2 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC (US) | 2010-08-24 | — | — | US | disclosed |
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K7 | PRKCQ 165/4885PRKCD 323/4885PIK3CA 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.