SCHEMBL29805035

SCHEMBL29805035

COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(N4CCCC4=O)cc2C)CC3)cc1

nearest known ligand 0.76

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.76
F2 P00734 3/20 0.76
SLC29A1 Q99808 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16730272 1.00 F10 (0.76) F10F2SLC29A1
SCHEMBL16730302 0.97 F10 (0.80) F10F2SLC29A1
SCHEMBL16730295 0.97 F10 (0.76) F10F2SLC29A1
SCHEMBL16730345 0.96 F10 (0.71) F10F2SLC29A1
SCHEMBL16730407 0.95 F10 (0.68) F10F2SLC29A1
SCHEMBL17572295 0.94 F10 (0.80) F10F2SLC29A1
SCHEMBL18028094 0.94 F10 (0.67) F10F2SLC29A1
SCHEMBL18028137 0.93 F10 (0.65) F10F2SLC29A1
SCHEMBL18028095 0.93 F10 (0.65) F10F2SLC29A1
SCHEMBL16730410 0.93 F10 (0.65) F10F2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111848610-B X crystal form of pyridine derivative, and preparation method and application thereof 浙江亚太药业股份有限公司 2022-11-18 CN disclosed
CN-111848610-B X crystal form of pyridine derivative, and preparation method and application thereof 浙江亚太药业股份有限公司 2022-11-18 CN disclosed
CN-109125320-B Pharmaceutical composition of pyridine compounds 浙江亚太药业股份有限公司 2022-09-16 CN disclosed