Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | PTK2 | Q05397 | 12/20 | 0.56 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.56 |
| ▸ | WEE1 | P30291 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26617098 | 1.00 | EGFR (0.57) | EGFRPTK2MAP4K1WEE1 | |
| SCHEMBL29805833 | 0.89 | MAP4K1 (0.64) | EGFRPTK2MAP4K1 | |
| SCHEMBL23533842 | 0.89 | MAP4K1 (0.64) | EGFRPTK2MAP4K1 | |
| SCHEMBL20214567 | 0.85 | MAP4K1 (0.74) | MAP4K1 | |
| SCHEMBL23533825 | 0.85 | MAP4K1 (0.72) | EGFRPTK2MAP4K1 | |
| SCHEMBL23533823 | 0.85 | MAP4K1 (0.72) | EGFRPTK2MAP4K1 | |
| SCHEMBL23534077 | 0.84 | EGFR (0.60) | EGFRPTK2MAP4K1 | |
| SCHEMBL29805918 | 0.84 | EGFR (0.60) | EGFRPTK2MAP4K1 | |
| SCHEMBL28852379 | 0.81 | PTK2 (0.58) | EGFRPTK2MAP4K1 | |
| SCHEMBL24073033 | 0.81 | EGFR (0.63) | EGFRPTK2MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118976029-A | Pharmaceutical composition for preventing or treating parkinson's disease or nonalcoholic steatohepatitis | 韩国化学研究院 | 2024-11-19 | — | — | CN | claimed |
| CN-114829344-A | Novel pyrimidine derivative and use thereof | 韩国化学研究院 | 2022-07-29 | — | — | CN | claimed |
| CN-118976029-A | Pharmaceutical composition for preventing or treating parkinson's disease or nonalcoholic steatohepatitis | 韩国化学研究院 | 2024-11-19 | — | — | CN | disclosed |
| CN-114829344-B | Pyrimidine derivatives and pharmaceutical compositions containing the same | 韩国化学研究院 | 2024-08-13 | — | — | CN | disclosed |