Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 14/20 | 0.77 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.71 |
| ▸ | INSR | P06213 | 3/20 | 0.66 |
| ▸ | IGF1R | P08069 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214436 | 1.00 | MAP4K1 (0.77) | MAP4K1ALKINSRIGF1R | |
| SCHEMBL20214556 | 1.00 | MAP4K1 (0.77) | MAP4K1ALKINSRIGF1R | |
| SCHEMBL24040087 | 0.90 | MAP4K1 (0.85) | MAP4K1ALKINSRIGF1R | |
| SCHEMBL24040051 | 0.90 | MAP4K1 (0.85) | MAP4K1ALKINSRIGF1R | |
| SCHEMBL30183975 | 0.90 | MAP4K1 (0.62) | MAP4K1ALKINSRIGF1R | |
| SCHEMBL25337779 | 0.90 | MAP4K1 (0.62) | MAP4K1ALKINSRIGF1R | |
| SCHEMBL25338542 | 0.89 | MAP4K1 (0.61) | MAP4K1ALKINSR | |
| SCHEMBL20214585 | 0.87 | MAP4K1 (1.00) | MAP4K1ALKINSRIGF1R | |
| SCHEMBL30184145 | 0.87 | ALK (0.62) | MAP4K1ALKINSR | |
| SCHEMBL24039925 | 0.86 | MAP4K1 (0.72) | MAP4K1ALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118976029-A | Pharmaceutical composition for preventing or treating parkinson's disease or nonalcoholic steatohepatitis | 韩国化学研究院 | 2024-11-19 | — | — | CN | claimed |
| CN-114829344-A | Novel pyrimidine derivative and use thereof | 韩国化学研究院 | 2022-07-29 | — | — | CN | claimed |
| CN-118976029-A | Pharmaceutical composition for preventing or treating parkinson's disease or nonalcoholic steatohepatitis | 韩国化学研究院 | 2024-11-19 | — | — | CN | disclosed |
| CN-114829344-B | Pyrimidine derivatives and pharmaceutical compositions containing the same | 韩国化学研究院 | 2024-08-13 | — | — | CN | disclosed |
| CN-114829344-A | Novel pyrimidine derivative and use thereof | 韩国化学研究院 | 2022-07-29 | — | — | CN | disclosed |