Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | MC3R | P41968 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640866 | 1.00 | KDM4E (0.48) | KDM4ENAPRTHCAR2BAZ2BADORA3 | |
| SCHEMBL4904135 | 0.83 | BAZ2B (0.52) | KDM4ENAPRTHCAR2BAZ2BADORA3 | |
| SCHEMBL12745729 | 0.78 | KDM4E (0.44) | KDM4ENAPRTHCAR2BAZ2BADORA3 | |
| SCHEMBL1412848 | 0.74 | KDM4E (0.59) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL14903392 | 0.73 | — | — | |
| SCHEMBL1442775 | 0.73 | — | — | |
| SCHEMBL1461124 | 0.72 | KDM4E (0.47) | KDM4ENAPRTHCAR2BAZ2BADORA3 | |
| Hydrochloric Acid SCHEMBL3134310 | 0.71 | BAZ2B (0.59) | KDM4ENAPRTHCAR2BAZ2BADORA3 | |
| SCHEMBL22859955 | 0.71 | KDM4E (0.50) | KDM4ENAPRTHCAR2BAZ2BADORA3 | |
| Hydrochloric Acid SCHEMBL7668906 | 0.71 | BAZ2B (0.59) | KDM4ENAPRTHCAR2BAZ2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003983-A1 | 1,2,4-OXADIAZOL-5-ONE DERIVATIVES FOR THE TREATMENT OF CANCER | Basilea Pharmaceutica International AG (CH) | 2022-06-01 | — | — | EP | disclosed |