Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930634 | 0.85 | SMPD1 (0.43) | SMPD1MTNR1AMAPTKDM4EHTT | |
| SCHEMBL23930570 | 0.82 | SMPD1 (0.37) | SMPD1MTNR1AMAPTKDM4EPTGS1 | |
| SCHEMBL17263376 | 0.80 | SMPD1 (0.49) | SMPD1MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL30210975 | 0.77 | SMPD1 (0.38) | SMPD1MTNR1AMAPTKDM4EALDH1A1 | |
| SCHEMBL24760612 | 0.75 | CHRM2 (0.46) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2759528 | 0.74 | CHRNA4 (0.50) | SMPD1MAPTKDM4EALDH1A1HTT | |
| SCHEMBL10521252 | 0.74 | SMPD1 (0.60) | SMPD1MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28775173 | 0.72 | NOTUM (0.41) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL15867782 | 0.72 | SMPD1 (0.42) | SMPD1ALDH1A1POLBCHRNA4 | |
| SCHEMBL22946700 | 0.71 | CDK1 (0.36) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006037-A1 | HETEROCYCLIC COMPOUND | Fimecs, Inc. (JP) | 2022-06-01 | — | — | EP | disclosed |