⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896827 | 0.88 | — | — | |
| SCHEMBL28135223 | 0.77 | — | — | |
| SCHEMBL1813417 | 0.74 | — | — | |
| SCHEMBL4641631 | 0.74 | — | — | |
| SCHEMBL1479975 | 0.74 | — | — | |
| SCHEMBL1127260 | 0.74 | — | — | |
| SCHEMBL9695415 | 0.74 | TDP1 (0.31) | — | |
| SCHEMBL8380131 | 0.72 | — | — | |
| SCHEMBL10545161 | 0.72 | — | — | |
| SCHEMBL4640293 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115175905-B | ZESTE enhancer homolog 2 inhibitors and uses thereof | 西藏海思科制药有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-115010617-B | Preparation method of iopamidol | 安徽普利药业有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-115010617-A | Preparation method of iopamidol | 安徽普利药业有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-107257813-A | Block copolymers having surface active anchoring groups, compositions and methods thereof | AZ电子材料卢森堡有限公司 | 2017-10-17 | — | — | CN | disclosed |
| EP-2975021-B1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | BRACCO IMAGING SPA (IT) | 2017-07-26 | — | — | EP | disclosed |
| EP-2975021-A1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | Bracco Imaging SPA (IT) | 2016-01-20 | — | — | EP | disclosed |
| EP-2608668-A1 | FUSED TRICYCLIC INHIBITORS OF MAMMALIAN TARGET OF RAPAMYCIN | Merck Sharp & Dohme Corp. (US) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012027234-A1 | FUSED TRICYCLIC INHIBITORS OF MAMMALIAN TARGET OF RAPAMYCIN | SCHERING CORPORATION (US) | 2012-03-01 | — | — | WO | disclosed |
| EP-1230219-A1 | AROMATIC SULFONS HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. Searle & Co. (US) | 2002-08-14 | — | — | EP | disclosed |
| EP-1042290-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-2000050396-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-1999025687-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 1999-05-27 | — | — | WO | disclosed |