Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL973366 | 1.00 | PIK3CD (0.61) | PIK3CD | |
| SCHEMBL976019 | 0.94 | PIK3CD (0.68) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL29808933 | 0.94 | PIK3CD (0.70) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL974585 | 0.94 | PIK3CD (0.70) | PIK3CD | |
| SCHEMBL976051 | 0.87 | PIK3CD (0.79) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL978122 | 0.85 | PIK3CD (0.71) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL29809231 | 0.85 | PIK3CD (0.71) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL29809054 | 0.85 | PIK3CD (0.58) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL975909 | 0.85 | PIK3CD (0.58) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL29808831 | 0.85 | PIK3CD (0.61) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11401280-B2 | Pyrimidinones as PI3K inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2022-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401280-B2 | Pyrimidinones as PI3K inhibitors | PIK3CA, PIK3CD, PIK3CB | PIK3CD 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.