Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | PRF1 | P14222 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172065 | 1.00 | GRM5 (0.56) | GRM5MEN1KMT2ASRD5A1PARP10 | |
| SCHEMBL17797550 | 0.90 | SRD5A1 (0.48) | GRM5MEN1KMT2ASRD5A1PARP10 | |
| SCHEMBL2016126 | 0.86 | MEN1 (0.53) | GRM5MEN1KMT2APARP10PARP1 | |
| SCHEMBL29407570 | 0.86 | MEN1 (0.53) | GRM5MEN1KMT2APARP10PARP1 | |
| SCHEMBL290250 | 0.82 | BRD4 (0.56) | MEN1KMT2ASRD5A1PARP10PARP11 | |
| SCHEMBL424393 | 0.81 | GRM5 (0.57) | GRM5MEN1KMT2ASRD5A1PARP10 | |
| SCHEMBL18053937 | 0.81 | GRM5 (0.57) | GRM5MEN1KMT2AAOC3OPRD1 | |
| SCHEMBL1817669 | 0.80 | GRM5 (0.61) | GRM5SRD5A1PRMT5WDR77 | |
| SCHEMBL19699194 | 0.79 | GRM5 (0.56) | GRM5MEN1KMT2ASRD5A1AOC3 | |
| SCHEMBL17244227 | 0.79 | PARP10 (0.47) | GRM5SRD5A1PARP10PARP11SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120077042-A | 3A,4,5, 6-tetrahydro-1H-pyrazolo [3,4-C ] pyridin-7 (7 AH) -one derivatives as factor XIIa inhibitors | 卡尔维斯塔制药有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-118451080-A | Tricyclic GPR65 modulators | 帕蒂奥斯治疗有限公司 | 2024-08-06 | — | — | CN | disclosed |
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-111655681-B | Heterocyclylamino-substituted triazoles as modulators of Rho-related protein kinases | 莱德克斯制药公共有限公司 | 2024-01-05 | — | — | CN | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |
| CN-113264920-B | CDK6 inhibitor of pyrimidine benzo six-membered ring parent nucleus and preparation method and application thereof | 中国药科大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-108707140-B | Protease C inhibitors | 勃林格殷格翰国际有限公司 | 2022-07-22 | — | — | CN | disclosed |