Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20441342 | 1.00 | KDM4E (0.59) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL29809220 | 1.00 | KDM4E (0.59) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL20441336 | 1.00 | KDM4E (0.59) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL21483311 | 1.00 | KDM4E (0.59) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL20441341 | 1.00 | KDM4E (0.59) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL20425224 | 0.88 | KDM4E (0.73) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL20425212 | 0.88 | KDM4E (0.73) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL20425214 | 0.88 | KDM4E (0.73) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL8258964 | 0.87 | KDM4E (0.72) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL10276380 | 0.87 | KDM4E (0.72) | KDM4EAPAF1POLBMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689873-B1 | ESTROGEN RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2022-09-14 | — | — | EP | disclosed |
| CN-110214140-B | Estrogen receptor modulators | 阿斯利康(瑞典)有限公司 | 2022-08-30 | — | — | CN | disclosed |