Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.63 |
| ▸ | JAK3 | P52333 | 9/20 | 0.60 |
| ▸ | BTK | Q06187 | 7/20 | 0.60 |
| ▸ | CD69 | Q07108 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809929 | 0.92 | BTK (0.71) | EGFRJAK3BTKCD69KCNH2 | |
| SCHEMBL24623409 | 0.92 | BTK (0.71) | EGFRJAK3BTKCD69KCNH2 | |
| SCHEMBL29809985 | 0.91 | BTK (0.69) | EGFRJAK3BTKCD69KCNH2 | |
| SCHEMBL29809896 | 0.90 | BTK (0.63) | EGFRJAK3BTKCD69KCNH2 | |
| SCHEMBL29809932 | 0.90 | BTK (0.60) | EGFRJAK3BTKCD69KCNH2 | |
| SCHEMBL29809868 | 0.89 | CTSC (0.65) | EGFRJAK3BTKCD69KCNH2 | |
| SCHEMBL29809871 | 0.83 | EGFR (0.57) | EGFRJAK3BTKCD69KCNH2 | |
| SCHEMBL14915495 | 0.82 | EGFR (0.87) | EGFRJAK3BTKCD69KCNH2 | |
| SCHEMBL29809872 | 0.82 | CTSC (0.61) | EGFRJAK3BTKCD69KCNH2 | |
| SCHEMBL29809870 | 0.82 | EGFR (0.73) | EGFRJAK3BTKJAK2BLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149856-A1 | COMPOUND FOR INHIBITING BRUTON'S TYROSINE KINASE, AND PHARMACEUTICAL USE THEREOF | 주식회사 온코빅스 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149856-A1 | COMPOUND FOR INHIBITING BRUTON'S TYROSINE KINASE, AND PHARMACEUTICAL USE THEREOF | 주식회사 온코빅스 | 2022-07-14 | — | — | WO | disclosed |