Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.49 |
| ▸ | JAK1 | P23458 | 5/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27238463 | 1.00 | TYK2 (0.49) | TYK2JAK1JAK2PDE4D | |
| SCHEMBL27238458 | 0.87 | TYK2 (0.50) | TYK2JAK1JAK2PDE4D | |
| SCHEMBL29766381 | 0.83 | TYK2 (0.49) | TYK2JAK1JAK2 | |
| SCHEMBL25316583 | 0.83 | TYK2 (0.49) | TYK2JAK1JAK2 | |
| SCHEMBL29810661 | 0.83 | TYK2 (0.62) | TYK2JAK2 | |
| SCHEMBL27238483 | 0.83 | TYK2 (0.62) | TYK2JAK2 | |
| SCHEMBL25897800 | 0.81 | TYK2 (0.49) | TYK2JAK1JAK2PDE4D | |
| SCHEMBL25316571 | 0.81 | TYK2 (0.50) | TYK2JAK1JAK2PDE4D | |
| SCHEMBL25897691 | 0.80 | TYK2 (0.45) | TYK2JAK1JAK2 | |
| SCHEMBL29766371 | 0.79 | TYK2 (0.48) | TYK2JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022175745-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | claimed |
| WO-2022175745-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | disclosed |